Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.900 strong 0.977 173 35 1982 2020
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.700 strong 0.966 119 12 2003 2020
Entrez Id: 1581
Gene Symbol: CYP7A1
CYP7A1
P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 91 0.576 0.615 2.5E-04 0.700 None 1.000 12 1 1993 2020
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase Enzyme 511 0.403 0.923 3.6E-19 0.040 None 1.000 4 0 2017 2020
Entrez Id: 5478
Gene Symbol: PPIA
PPIA
P62937 peptidylprolyl isomerase A 180 0.510 0.769 0.56 0.030 None 0.667 3 0 2016 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.700 None 0.957 94 4 1985 2019
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.900 strong 0.985 66 5 1987 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.400 None 0.957 23 0 1994 2019
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
P04035 3-hydroxy-3-methylglutaryl-CoA reductase 154 0.529 0.692 1.00 0.600 None 1.000 20 1 1978 2019
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.500 None 0.923 13 1 1995 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 12 0 2003 2019
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.680 None 1.000 9 0 1993 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.080 None 0.875 8 0 1999 2019
Entrez Id: 29881
Gene Symbol: NPC1L1
NPC1L1
Q9UHC9 NPC1 like intracellular cholesterol transporter 1 Transporter 40 0.656 0.423 2.3E-20 0.080 None 1.000 8 0 2005 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.080 None 1.000 8 0 2015 2019
Entrez Id: 6721
Gene Symbol: SREBF2
SREBF2
Q12772 sterol regulatory element binding transcription factor 2 112 0.566 0.577 0.21 0.260 None 0.857 7 0 2002 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.070 None 1.000 7 0 2007 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.350 None 0.833 6 0 1999 2019
Entrez Id: 345
Gene Symbol: APOC3
APOC3
P02656 apolipoprotein C3 153 0.531 0.731 1.0E-02 0.460 None 1.000 6 0 2001 2019
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
Q9H222 ATP binding cassette subfamily G member 5 Transporter 108 0.592 0.577 3.1E-21 0.460 strong 1.000 6 2 2004 2019
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.360 None 0.833 6 0 1990 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.150 None 1.000 5 0 1985 2019
Entrez Id: 949
Gene Symbol: SCARB1
SCARB1
Q8WTV0 scavenger receptor class B member 1 Receptor 116 0.559 0.731 6.6E-02 0.350 None 1.000 5 1 2003 2019
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
P11150 lipase C, hepatic type Enzyme 120 0.585 0.654 3.3E-07 0.540 None 1.000 5 0 1995 2019
Entrez Id: 10599
Gene Symbol: SLCO1B1
SLCO1B1
Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 151 0.538 0.731 1.1E-21 0.040 None 1.000 4 1 2012 2019